pKB values of the alpha-2 adrenoceptor antagonist yohimbine and I1/alpha-2 receptor antagonist efaroxan against agonists
| Drug | pKB | 95% CI | n |
|---|---|---|---|
| Yohimbine 3 μM | |||
| Against moxonidine | 7.27 | 6.60–7.94 | 4 |
| Against rilmenidine | 7.07 | 6.61–7.54 | 5 |
| Against UK 14,304 | 7.38 | 6.75–7.99 | 4 |
| Efaroxan 0.01 μM | |||
| Against moxonidine | 7.66 | 6.92–8.40 | 5 |
| Against UK 14,304 | 8.03 | 7.73–8.33 | 5 |
| Efaroxan 1 μM | |||
| Against moxonidine | 7.86 | 7.39–8.33 | 4 |
| Against UK 14,304 | 7.96 | 7.63–8.29 | 4 |