Table 3

The open field test (mean values ± S.E.M.): Behavioral effects in adult male rats treated neonatally with Lu 10-134-C or saline

Open Field TestSalineLu 10-134-C
2.5 mg/kg5.0 mg/kg10 mg/kg15 mg/kg
% time in peripheral arena96.0  ± 1.096.0  ± 1.097.0  ± 1.095.0  ± 0.895.0  ± 1.5
% time in central arena4.0  ± 1.04.0  ± 1.03.0  ± 1.05.0  ± 0.85.0  ± 1.5
Traveled distance in peripheral arena (cm)4600  ± 3404200  ± 4104700  ± 2304400  ± 3704300  ± 660
Traveled distance in central arena (cm)330  ± 80330  ± 91490  ± 69450  ± 80390  ± 77