Effects of Lu 28-179 and diazepam on spontaneous locomotor activity and performance on a horizontal wire in mice. For details, see “Materials and Methods”
| Drug (treatment time) | ED50 (μmol/kg s.c.) (95% confidence interval) | |
|---|---|---|
| Locomotor Activity | Performance on Horizontal Wire | |
| Lu 28-179 (2 h) | >73 | >70 |
| Diazepam (30 min) | 33 | 5.2 |
| (12–89) | (2.7–9.9) | |