Table 3

Effects of Lu 28-179 and diazepam on footshock-induced ultrasonic vocalization in the rat and isolation-induced aggressive behavior of male mice. For details, see “Materials and Methods”

Drug (treatment time)ED50 (μmol/kg s.c.) (95% confidence interval)
Footshock-Induced Ultrasonic VocalizationIsolation-Induced Aggression
Lu 28-179 (2 h)>35>35
Diazepam (30 min) 13 26
(8.1–21)(10–68)