Table 4

Mean peak ratings (±S.E.M.) of VAS adjectives sensitive to 0.3 mg buprenorphine and/or 10 mg morphine (ratings correspond to saline, buprenorphine and morphine, respectively)

SalineBuprenorphineMorphine
Coasting (spaced out)17.9  (6.9)65.3  (8.6)4-b 44.1  (9.5)4-b
Confused8.1  (5.6)31.8  (7.0)4-b 13.3  (5.7)
Difficulty
Concentrating9.4  (5.6)66.4  (6.4)4-b 4-c 36.3  (8.6)4-b
Dizzy4.0  (1.2)62.3  (7.8)4-b 4-c 23.0  (5.9)4-b
Drunk2.7  (0.8)28.0  (7.9)4-b 15.6  (4.8)
Feel bad10.6  (3.3)35.1  (7.6)4-b 20.6  (7.4)
Floating12.4  (5.7)59.3  (8.2)4-b 4-c 41.0  (8.8)4-b
Having pleasant bodily sensations21.7  (7.2)44.4  (8.5)4-b 37.5  (7.4)4-b
Having pleasant thoughts40.0  (6.7)53.2  (7.8)4-b 45.7  (6.7)
Having unpleasant bodily sensations13.1  (3.9)41.2  (8.9)4-b 19.2  (5.2)
Heavy, sluggish feeling18.3  (7.1)63.0  (9.3)4-b 53.7  (8.8)4-b
High12.9  (6.4)61.9  (8.8)4-b 4-c 36.2  (8.6)4-b
Hungry4-a 71.1  (6.6)43.0  (9.8)4-b 58.3  (8.9)
Lightheaded12.6  (5.9)65.9  (7.3)4-b 4-c 39.8  (8.0)4-b
Nauseous4.6  (1.7)45.9  (10.3)4-b 16.7  (4.9)
Sedated30.3  (7.3)63.0  (7.8)4-b 63.6  (9.1)4-b
Sleepy28.7  (6.8)69.3  (8.4)4-b 4-c 48.8  (9.4)4-b
Tingling8.4  (3.1)42.0  (9.0)4-b 25.3  (7.9)
  • 4-a Trough rating.

  • 4-b P < .05 compared with saline.

  • 4-c Buprenorphine rating significantly different from morphine rating.