Table 2

Mean peak or trough ratings (±S.E.M.) of ARCI scales sensitive to 0.3 mg buprenorphine and/or 10 mg morphine (ratings correspond to saline, buprenorphine and morphine, respectively)

ScaleSalineBuprenorphineMorphine
PCAG5.3  (0.9)11.4  (0.6)2-a 9.8  (0.6)2-a
BG2-b 5.4  (0.4)1.9  (0.4)2-a 2-c 3.3  (0.4)2-a
AMP3.7  (0.6)4.5  (0.5)4.6  (0.5)2-a
LSD4.1  (0.6)8.1  (0.6)2-a 2-c 6.4  (0.6)2-a
  • 2-a P < .05 compared with saline.

  • 2-b Trough rating.

  • 2-c Buprenorphine score significantly different from morphine score.