Functional recovery after sciatic nerve crush in saline-treated and FK506-treated rats
| Saline | FK506 | |||
|---|---|---|---|---|
| 2 mg/kg | 5 mg/kg | 10 mg/kg | ||
| Days to onset1-a | 16.8 ± 0.21-c | 15 ± 0* | 14 ± 0* , † | 14.3 ± 0.3* |
| Days to walking1-b | 17.8 ± 0.2 | 16 ± 0* | 15 ± 0* , †† | 15.3 ± 0.3* , † |
↵1-a Number of days until initial signs of return of toe movement.
↵1-b Number of days until initial return of ability to walk on hind feet and toes.
↵1-c Values are mean ± S.E.M.
* P < .0001, compared with saline group (one-way ANOVA followed by FLSD).
† P < .01, compared with 2-mg/kg group (one-way ANOVA followed by FLSD).
†† P < .001, compared with 2-mg/kg group (one-way ANOVA followed by FLSD).