Receptor | Affinity Ki |
---|---|
nm | |
D4.2 | 3.6 ± 0.6 |
5-HT1A | 180 ± 10 |
5-HT3 | 7502-b |
D2(primate) | 2230 ± 300 |
Sigma | 2490 |
a2 | 2520 |
H1 | 37002-b |
↵2-a Receptors at which NGD 94-1 was inactive (i.e., less than 50% inhibition of specific binding observed with 10 μM NGD 94-1): D1, D3, D5, a1, 5-HT2A, 5-HT2C, NMDA (PCP), NPY1, NPY2, A1,b A2,b beta-adrenergic (nonselective),b glycine,b H3,bmuscarinic (nonselective)b NMDA (agonist site)b and opiate (nonselective).b
↵2-b Approximate IC50 value from semiquantitative Panlabs data.