Table 1

Effects of vehicle and VIP (1, 10 and 100 pmol) microinjected into the nAmb on intragastric PRIGP and PCA and GCCA as well as on MAP in five animals1-a

TreatmentPRIGPPCAGCCAMAP
cm H2O MMI mm Hg
Vehicle0.4  ± 0.20.5  ± 0.80.1  ± 0.40  ± 0
VIP (1 pmol)0.6  ± 0.4−1.8  ± 1.3−0.1  ± 0.2−2.0  ± 1.2
VIP (10 pmol)0.6  ± 0.1−0.8  ± 1.20.5  ± 0.40  ± 1.6
VIP (100 pmol)0.6  ± 0.10.6  ± 1.0−0.2  ± 0.61  ± 1
  • 1-a Values are means ± S.E. Abbreviations: PRIGP, pressure peak response; PCA, pyloric circular muscle contractile activity; GCCA, greater curvature longitudinal muscle contractile activity.