Table 3

Percentages of maximal displacement of [3H]oxo-M by CHI

% Maximal Displacement (±SD)
Rat brain stemRat cortexHuman brain stemHuman cortex
Parathion * * * *
Paraoxon71a (±7)83a (±4)27b (±10)32b (±18)
Physostigmine63c (±12)83d (±5)92e (±11)95f (±6)
PSP69g (±7)77g (±8)25h (±16) *
  • * A percentage of maximal displacement could not be determined, because of limited displacement at the highest concentrations used, i.e. 10 μM parathion and 100 μM PSP.

  • Data are means of three to six triplicate experiments ± S.D. Different superscript letters at the same row indicate significant differences. a vs. b: P ≤ .01; c vs. eand d vs. f: P < .02; g vs. h: P < .02.