% Maximal Displacement (±SD) | ||||
---|---|---|---|---|
Rat brain stem | Rat cortex | Human brain stem | Human cortex | |
Parathion | * | * | * | * |
Paraoxon | 71a (±7) | 83a (±4) | 27b (±10) | 32b (±18) |
Physostigmine | 63c (±12) | 83d (±5) | 92e (±11) | 95f (±6) |
PSP | 69g (±7) | 77g (±8) | 25h (±16) | * |
* A percentage of maximal displacement could not be determined, because of limited displacement at the highest concentrations used, i.e. 10 μM parathion and 100 μM PSP.
Data are means of three to six triplicate experiments ± S.D. Different superscript letters at the same row indicate significant differences. a vs. b: P ≤ .01; c vs. eand d vs. f: P < .02; g vs. h: P < .02.