The effect of 5β-THDOC (1 mg/kg) on 3α,5α-P induced LRR in mice
| Treatment | ED50 | Confidence interval |
|---|---|---|
| mg/kg | ||
| 3α,5α-P | 3.5 | 2.5–4.1 |
| 3α,5α-P + 5β-THDOC | 7.01-a | 5.7–8.1 |
↵1-a The potency ratio of the ED50 values from the two treatment groups is significant by the χ2 test. Data are from three independent determinations with 7 to 10 animals per dose tested and five doses per determination.