Table 1

Base-line values of MAP and HR in experimental groups1-a

StrainPharmacological BlockadeMAPHR
Base LineAfter BlockadeBase LineAfter Blockade
mm Hg bpm
SHRNone166  ± 5–412  ± 13–
SHRHexamethonium166  ± 4104  ± 4* 407  ± 17380  ± 15*
SHRPhentolamine155  ± 1290  ± 9* 385  ± 29505  ± 26*
SHR l-NMMA156  ± 9176  ± 10* 448  ± 12401  ± 15*
SHRPropranolol176  ± 6201  ± 8* 410  ± 16334  ± 6*
SHRAtropine167  ± 8166  ± 8406  ± 12514  ± 10*
SHRHexamethonium + phentolamine + propranolol176  ± 12122  ± 11* 417  ± 29286  ± 10*
WKYNone81  ± 3† –365  ± 20–

  • ↵1-a Values are expressed as means ± S.E.M.

  • * P < .05 vs. base line.

  • † P < .01 vs. SHR base-line groups.