Table 2

Comparison of effects of morphine (0.1 μM) and clonidine (0.3 μM) in S cells from guinea pigs implanted with placebo or morphine pellets

PretreatmentMorphineClonidine
Hyperpolarization (mV)Hyperpolarization (mV)Δ Resistance (MΩ)
Placebo6.1  ± 0.77.3  ± 1.1−29.1  ± 7.9
Morphine7.5  ± 0.96.2  ± 0.9−16.3  ± 5.6
  • Values are means of 8 cells from placebo preparations and 16 cells from morphine-pretreated guinea pigs.