Table 3

Effects of CI988 (3, 6 and 9 mg/kg i.p.) on carrageenin-induced spinal c-Fos expression

DrugsFos-LI Neurons Induced 90 min after Intraplantar Carrageenin
TotalSuperficial laminae
% of control
CI988 (3 mg/kg i.p.)97  ± 597  ± 2
CI988 (6 mg/kg i.p.)97  ± 4108  ± 2
CI988 (9 mg/kg i.p.)96  ± 4104  ± 3

The results are expressed as percentage of the control carrageenin group ± S.E.M..

  • Significance, compared with the control carrageenin group, was assessed using analysis of variance and protected least-significant difference Fisher’s test.