Compound | Ki (nM) ±S.E.M.* | N |
---|---|---|
Antagonists | ||
Devazepide | >300 | 5 |
L-365,260 | 4.14 ± 0.68 | 5 |
CI-988 | 2.39 ± 1.27 | 4 |
CP-212,454 | 0.65 ± 0.60 | 3 |
CP-310,713 | 0.23 | 2 |
Agonists | ||
Pentagastrin | 0.3 ± 0.13† | 5 |
* Ki values were calculated as described in “Methods” and are the means of the indicated number of experiments (N).
† EC50 for pentagastrin-stimulated phosphatidylinositol turnover in rat AR 4-2J pancreatoma cells expressing CCKB-receptors.