PD156707 | Coronary Artery | Mammary Artery | Saphenous Vein |
---|---|---|---|
nM | |||
3 | 9.17 ± 0.25 (n = 8) | 9.23 ± 0.27 (n = 5) | |
10 | 8.23 ± 0.26 (n = 6) | 8.42 ± 0.18 (n = 9) | 8.96 ± 0.20 (n = 7) |
30 | 8.30 ± 0.14 (n = 8) | 8.24 ± 0.11 (n = 8) | 8.62 ± 0.22 (n = 8) |
100 | 7.94 ± 0.13 (n = 8) | 8.05 ± 0.14 (n = 6) | 8.64 ± 0.35 (n = 5) |
300 | 7.62 ± 0.11 (n = 5) | 7.91 ± 0.31 (n = 3) | 8.11 ± 0.30 (n = 6) |
Mean | 8.07 ± 0.09 | 8.45 ± 0.11 | 8.70 ± 0.13 |
For each concentration of PD156707 data are the pA2 values (mean ± S.E.M., from n individuals) estimated from the Gaddum-Schild equation assuming a slope of 1, where pA2 = log10{[concentration ratio − 1]/concentration PD156707 (M)}.