Bmax | Kd | |||||
---|---|---|---|---|---|---|
Sham | ADX | ADX + DEXA | SHAM | ADX | ADX + DEXA | |
fmol/mg gray matter | nM | |||||
Caudate putamen | 103.2 ± 2.8 | 86.3 ± 1.8* †† † | 117.7 ± 5.7 | 2.9 ± 0.11 | 2.4 ± 0.17 | 2.9 ± 0.29 |
Stratum radiatum of CA1 | 372.4 ± 12.6 | 391.9 ± 11.0 | 179.9 ± 18.4 | 3.1 ± 0.18 | 2.3 ± 0.17* | 2.1 ± 0.23 |
Stratum radiatum of CA3 | 209.6 ± 10.6 | 190.0 ± 14.5† | 239.5 ± 7.1 | 2.1 ± 0.23 | 1.7 ± 0.30 | 1.9 ± 0.13 |
Granular layer in dentate gyrus | 202.0 ± 7.2 | 180.7 ± 10.5 | 198.5 ± 5.2 | 2.9 ± 0.22 | 2.3 ± 0.30 | 2.2 ± 0.13 |
Molecular layer in cerebellum | 300.8 ± 6.2 | 260.2 ± 6.2†† | 328 ± 11.8 | 1.3 ± 0.12 | 1.4 ± 0.08 | 1.4 ± 0.12 |
Frontoparietal cortex | 227.6 ± 5.5 | 171.5 ± 3.7*** †† † | 245.1 ± 9.7 | 2.3 ± 0.12 | 1.8 ± 0.09† | 2.7 ± 0.22 |
Occipital cortex | 267.8 ± 16.1 | 221.9 ± 2.5 | 271.8 ± 11.2 | 1.7 ± 0.24 | 1.5 ± 0.05 | 1.7 ± 0.17 |
Ventrolateral nucleus of thalamus | 92.2 ± 4.2 | 84.1 ± 6.0† | 112.5 ± 4.6 | 1.1 ± 0.12 | 1.1 ± 0.20 | 1.0 ± 0.11 |
The number of animals in each group is between six and nine.
* P < .05 vs. sham.
*** P < .001 vs. sham.
† P < .05 vs. adrenalectomized and dexamethasone-treated.
†† P < .01 vs. adrenalectomized and dexamethasone-treated.
††† P < .001 vs. adrenalectomized and dexamethasone-treated.