Table 2

Regional segmental length and function for the AAR throughout the experiment

TimeEDSLESSLSegmental ShorteningSegmental Workβ
VEH2-aCGSVEHCGSVEHCGSVEHCGSVEHCGS
mm mm % mm Hg · mm
Control15.7  ± 1.313.4  ± 1.412.6  ± 1.111.3  ± 1.319.6  ± 2.016.5  ± 1.6257.2  ± 41.0186.2  ± 21.00.21  ± 0.030.36  ± 0.05*
Ischemia19.2  ± 1.7 15.7  ± 1.9 19.8  ± 1.7 15.9  ± 1.7 −3.6  ± 0.7 −2.4  ± 1.7 67.2  ± 26.8 67.1  ± 24.1 0.51  ± 0.180.69  ± 0.18
Reperfusion
 15 min16.9  ± 1.613.9  ± 1.717.4  ± 1.7 13.8  ± 1.6 −3.2  ± 0.9−0.2  ± 2.483.4  ± 14.972.8  ± 34.10.54  ± 0.120.53  ± 0.11
 60 min17.1  ± 1.613.7  ± 1.517.6  ± 1.713.4  ± 1.4−3.3  ± 1.31.8  ± 2.267.1  ± 17.967.1  ± 24.10.66  ± 0.200.55  ± 0.14
 120 min16.6  ± 1.414.3  ± 1.317.4  ± 1.414.3  ± 1.2−5.5  ± 1.8−1.1  ± 1.9 42.1  ± 16.636.4  ± 26.1 0.53  ± 0.130.49  ± 0.12
 180 min16.6  ± 1.414.3  ± 1.317.3  ± 1.414.3  ± 1.2−4.5  ± 1.4−1.0  ± 1.644.3  ± 13.939.1  ± 25.80.49  ± 0.140.57  ± 0.18
  • 2-a VEH, vehicle-treated; CGS, CGS-21680-treated. Values expressed as mean ± S.E.M.

  • * P < .05 vs. vehicle-treated.

  • † P < .05 vs. prior time point.