TABLE 2

Effect of combinatorial treatment of probucol and cilostazol on plasma cholesterol level

Values are mean ± S.E.M.

ControlVehicleProbucolCilostazolProbucol + Cilostazol
n = 11n = 10n = 10n = 10n = 11
Total cholesterol474.73 ± 27.75759.60 ± 32.04**230.70 ± 24.94##730.40 ± 69.43171.64 ± 6.88##
LDL cholesterol321.64 ± 24.70663.20 ± 73.93**170.40 ± 16.88##627.50 ± 67.35130.18 ± 4.94##
HDL cholesterol132.27 ± 5.93177.90 ± 11.96**53.50 ± 3.52##177.30 ± 16.7743.36 ± 1.23##
Triglyceride82.46 ± 12.2958.60 ± 7.0058.70 ± 9.9638.20 ± 4.1635.09 ± 4.98#

  • ↵** , P < 0.01 versus age-matched ApoE KO mice without HFD (Control).

  • ↵# , P < 0.05 and ##, P < 0.01 versus age- and diet-matched ApoE KO mice (Vehicle).