TABLE 1
List of the main notations
| Notation | Meaning |
|---|---|
| D | Dataset of the 19 considered JAK2V617F patients |
| i | Index of the patient |
| t | Time |
| T | Assimilation time (until which observations are considered for calibrating the model) |
| τ | Patient’s age at which the treatment could be interrupted |
 | Dataset of patient i |
 | Data of all patients except patient i |
 | Observations of patient i, before time T, used for calibrating the model |
 | Observations of patient i not used for the model calibration |
| d | Normalized dose of IFNα (between 0 and 1; 1 corresponding to 180 μg/week) |
| z(d) | IFNα toxicity (as a function of the dose d) |
| M(τ) | Amount of IFNα administered over [T, τ] (when penalizing for high dose) |