Peptide | Dose | Cmax/Dose | AUC∞/Unit Dose | Tmax | Terminal Half-Life | Fsc | n |
---|---|---|---|---|---|---|---|
mg/kg | (μg/ml)/(mg/kg) | (μg/ml*h)/(mg/kg) | h | h | % | ||
Apraglutide | 1 | 1.96 ± 0.1 | 45.2 ± 2.0 | 6.7 ± 0.6 | 11.7 ± 1.4 | 74 ± 3 | 3 |
5 | 0.90 ± 0.1 | 32.6 ± 1.7 | 7.5 ± 1.0 | 22.5 ± 1.3 | 54 ± 3 | 4 | |
Teduglutide | 1 | 0.54 ± 0.1 | 1.1 ± 0.2 | 0.6 ± 0.4 | 0.5 ± 0.1 | 63 ± 12 | 3 |
5 | 0.54 ± 0.1 | 1.3 ± 03 | 1.0 ± 0.0 | 0.5 ± 0.0 | 74 ± 17 | 4 |