Amino acid sequence and molecular weight of hGLP-2 and GLP-2 analogs
Amino acid substitutions relative to native hGLP-2 are shown in bold underlined letters.
| Peptide | Mol. wt. | Amino Acid Sequence | |||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | |||
| hGLP-2 | 3766 | H | A | D | G | S | F | S | D | E | M | N | T | I | L | D | N | L | A | A | R | D | F | I | N | W | L | I | Q | T | K | I | T | D | OH |
| Glepaglutide | 4316 | H | G | E | G | T | F | S | S | E | L | A | T | I | L | D | A | L | A | A | R | D | F | I | A | W | L | I | A | T | K | I | T | D | KKKKKKNH2 |
| Teduglutide | 3752 | H | G | D | G | S | F | S | D | E | M | N | T | I | L | D | N | L | A | A | R | D | F | I | N | W | L | I | Q | T | K | I | T | D | OH |
| Apraglutide | 3765 | H | G | D | G | S | F | S | D | E | Nle | f | T | I | L | D | L | L | A | A | R | D | F | I | N | W | L | I | Q | T | K | I | T | D | NH2 |
f, D-phenylalanine.