TABLE 2

Echocardiographic parameters in NLRP3-KO mice after LPS injection Values are means ± S.E.

	NLRP3-KO NS–Vehicle (n = 10)	NLRP3-KO NS–AUB (n = 10)	WT–LPS (n = 10)	NLRP3-KO LPS–Vehicle (n = 10)	NLRP3-KO LPS–AUB (n = 10)
LVESd	3.4 ± 0.16	3.48 ± 0.21	3.78 ± 0.44	3.50 ± 0.25	3.58 ± 0.25
LVEDd	2.43 ± 0.23	2.33 ± 0.21	3.20 ± 0.43^*	2.86 ± 0.12^*^#	2.89 ± 0.11^*^#
LVPWd	0.76 ± 0.09	0.77 ± 0.09	0.76 ± 0.13	0.76 ± 0.07	0.75 ± 0.06
LVPWs	0.55 ± 0.06	0.54 ± 0.05	0.51 ± 0.09	0.57 ± 0.06	0.56 ± 0.07
LVEF	69.4 ± 7.8	71.6 ± 5.4	37 ± 4.4^*	59.5 ± 8.7^*^#	60.9 ± 8.7^*^#
LVFS	34.3 ± 6.4	36.4 ± 5.1	15 ± 2.6^*	23.3 ± 2.7^*^#	23.9 ± 3.2^*^#

LVPWd, LV end-diastolic posterior wall thickness; LVPWs, LV end-systolic posterior wall thickness; NS, normal saline; WT, wild type.
↵^* P < 0.05 for difference from NLRP3-KO/NS–vehicle group.
↵^# P < 0.05 vs. WT–LPS group.