[125I]RTI-55 specific binding in subcellular fractions
Data represent mean ± S.E.M. for each subcellular fraction from three independent experiments, using pooled tissue from six to eight untreated Taar1 HET mice with one to two independently pooled preparations of tissue per experiment.
| Fraction | [125I]RTI-55 Binding ± S.E.M. |
|---|---|
| pmol/mg protein | |
| Synaptosomal | 3.9 ± 0.4* |
| Membrane-associated | 6.2 ± 0.5* |
| Vesicular | 0.6 ± 0.1* |
* P < 0.01; fractions significantly differed from each other.