List of model parameters along with their numerical values and sources
| Parameter | Description (unit) | Estimate | CV% |
|---|---|---|---|
| Jlung | Transmigration rate for each tissue (1/h) | 1843.0 | 15.4 |
| Jheart | 34.9 | 17.2 | |
| Jkidney | 87.3 | 37.9 | |
| Jbrain | 1.4 | 21.2 | |
| Jmuscle | 0.5 | 19.7 | |
| Jbone | 82.6 | 16.7 | |
| Jtumor | 0.6 | 18.6 | |
| Jskin | 0.6 | 18.7 | |
| Jfat | 1.6 | 18.5 | |
| JSI | 12.9 | 17.1 | |
| JLI | 5.2 | 18.1 | |
| Jspleen | 114.0 | 33.8 | |
| Jliver | 126.9 | 18.9 | |
| Jpancreas | 10.0 | 20.0 | |
| Jother | 86.8 | 17.7 | |
| Rkidney | Retention factor | 3.9 | 37.9 |
| Rspleen | 9.8 | 34.8 | |
| Rliver | 2.5 | 18.4 | |
| Elung | Elimination rate (1/h) | 0.84 | Fixed (Zhu et al., 1996) |
| Ftissue | Fraction of T cells recirculated to lymph node | 1 | Fixed (assumption) |
| Qtissue, Ltissue, Vtissue | Physiologic blood flows, lymph flows, and tissue volumes for each mouse tissue (ml/h, ml/h, ml) | Fixed (Shah and Betts, 2012) | |
| Qtumor | Tumor blood flow (ml/h) | 6 | Fixed (Zhu et al., 1996) |
| Vtumor | Tumor volume (ml or g) | 0.45 | Fixed (radiusā¼3.85 mm) |