Heart weight, body weight, the heart weight/body weight ratio and left ventricular (LV) mass in diabetic and control groups (n = 8/group)
| Group | HeartWeight (HW) | Body Weight (BW) | HW/BW Ratio | LV Mass |
|---|---|---|---|---|
| g | g | mg/kg | ||
| Sham | 0.44 ± 0.02 | 278.22 ± 8.00 | 1.60 ± 0.07 | 1554.00 ± 64.73 |
| OVX | 0.57 ± 0.04 | 324.00 ± 9.06 | 1.74 ± 0.09 | 1736.00 ± 113.30 |
| OVX + E2 | 0.54 ± 0.03 | 293.50 ± 6.40 | 1.83 ± 0.14 | 1772.00 ± 150.90 |
| Male | 0.95 ± 0.01* | 475.11 ± 10.88* | 1.99 ± 0.20 | 1591.00 ± 101.70 |
| Diabetic sham | 0.74 ± 0.05 | 253.40 ± 16.00 | 3.01 ± 0.21*,** | 2531.00 ± 315.90*,** |
| Diabetic OVX | 0.56 ± 0.04 | 313.89 ± 10.37 | 1.87 ± 0.11 | 1789.00 ± 103.70 |
| Diabetic OVX + E2 | 0.67 ± 0.04 | 278.13 ± 12.68 | 2.43 ± 0.19*,** | 2037.00 ± 67.86*,** |
| Diabetic male | 0.85 ± 0.07 | 451.17 ± 21.23* | 1.95 ± 0.12 | 1978.00 ± 96.64 |
E2, estrogen/estradiol; OVX, ovariectomy.
↵* Denotes significant (P < 0.05) differences between a diabetic and its respective healthy group.
↵** Denotes intergroup significant differences (P < 0.05). The HW/BW ratio and LV mass are higher in the diabetic estrogen-replete groups compared with estrogen-depleted groups.