Basal dialysate levels (mean ± S.E.M.) monitored in the different experimental conditions/treatment groups
| Treatment in 6-OHDA Lesioned Rats | SNr GABA | Striatum | |
|---|---|---|---|
| GABA | Glutamate | ||
| nM | nM | nM | |
| Saline/l-DOPA (n = 15) | 3.67 ± 0.41 | 4.61 ± 0.90 | 117.01 ± 16.64 |
| Safinamide/l-DOPA (n = 13) | 3.18 ± 0.56* | 5.10 ± 1.11 | 133.43 ± 22.68 |
| Saline (n = 10) | 5.39 ± 0.86 | 5.92 ± 0.11 | 123.87 ± 19.74 |
↵* P < 0.05 from 6-OHDA saline.