TABLE 2

Intronic SNPs associated with NAPQI-induced hepatotoxicity [Moyer et al. (2011), n = 176]

SNP	Gene	Name	Alleles^{^a}	MAF	Category	P Value^{^b}
rs1532815	LMX1A	LIM homeobox transcription factor 1 alpha	A/T	0.33	Intron	6.04E−7
rs3795578	ETNK2	Ethanolamine kinase 2	C/T	0.40	Intron	7.18E−6
rs3825924	ALDH1A3	Aldehyde dehydrogenase 1 family member A3	C/T	0.21	Intron	1.73E−5
rs1343151	IL23R	Interleukin 23 receptor	G/A	0.34	Intron	1.91E−5
rs17640676	KCNJ3	Potassium voltage-gated channel subfamily J member 3	G/T	0.23	Intron	2.09E−5
rs4869233	MCTP1	Multiple C2 and transmembrane domain containing 1	T/C	0.32	Intron	2.28E−5
rs16851554	SPAG16	Sperm associated antigen 16	T/G	0.15	Intron	2.46E−5
rs3208829	LAMA4	Laminin subunit alpha 4	C/G	0.16	Intron	2.54E−5
rs11153350	RFPL4B	Ret finger protein like 4B	G/A	0.15	Intron	2.54E−5
rs3746923	UBASH3A	Ubiquitin associated and SH3 domain containing A	C/T	0.43	Intron	2.56E−5