Isoforms | Epalrestat | HET0016 | 17-ODYA |
---|---|---|---|
CYP4A11 | 1.82 ± 0.04 (1.00) | 0.0182 ± 0.0010 (1.00) | 7.88 ± 0.18 (1.00) |
CYP4F2 | 35.9 ± 1.3 (19.7) | 0.0137 ± 0.0003 (0.753) | 5.70 ± 0.35 (0.723) |
CYP4F3B | 19.9 ± 1.0 (10.9) | 0.102 ± 0.005 (5.60) | 7.97 ± 0.28 (1.01) |
CYP4F12 | 38.7 ± 2.3 (21.3) | 3.36 ± 0.24 (185) | 17.7 ± 0.6 (2.25) |