Effects of solriamfetol in receptor binding assays
| Receptor Site | Ki (nM) |
|---|---|
| DA D1 | >10,000 |
| DA D2 | >10,000 |
| DA D3 | >10,000 |
| DA D4 | >10,000 |
| DA D5 | >10,000 |
| 5-HT1A | 3558 |
| 5-HT2A | >10,000 |
| 5-HT3A | >10,000 |
| 5-HT2C | >10,000 |
| 5-HT7 | >10,000 |
| α1A | >10,000 |
| α2A | 10,470 |
| α2B | 2684 |
| α2C | >100,000 |
| Histamine H1 | >10,000 |
| Histamine H2 | >10,000 |
| Histamine H3 | >10,000 |
| Neurokinin NK1 | >10,000 |
| nAChR | >10,000 |
| CCK1 | >10,000 |
CCK, cholecystokinin; nAChR, nicotinic acetylcholine receptors.