TABLE 2

Relaxation of the femoral artery to selexipag and ACT-333679

Data are presented as the mean ± S.E.M.

Contractile agentSelexipagACT-333679
pEC50
 PGF2α5.4 ± 0.15.5 ± 0.1
 Phenylephrine5.5 ± 0.15.6 ± 0.1
Emax
 PGF2α113.3 ± 5.4126.9 ± 7.0
 Phenylephrine116.6 ± 6.6121.0 ± 6.6