Model | False positives | True positives | True negatives | False negatives | Concordance | Sensitivity | Specificity | PPV | Adjusted PPV (30% prev) | Value added PPV | NPV | Adjusted NPV (30% prev) | Value added NPV | PRU positive | PRU negative |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Zebrafish CPP | 4 | 6 | 8 | 6 | 0.58 (0.39, 0.76) | 0.5 (0.25, 0.75) | 0.67 (0.39, 0.86) | 0.6 (0.31, 0.83) | 0.39 (0.19, 0.7) | 0.09 (-0.11, 0.4) | 0.57 (0.33, 0.79) | 0.76 (0.59, 0.88) | 0.06 (-0.11, 0.18) | 0.13 (-0.16, 0.57) | 0.19 (-0.37, 0.59) |
Rat CPP | 8 | 9 | 2 | 2 | 0.52 (0.32, 0.72) | 0.82 (0.52, 0.95) | 0.20 (0.06, 0.51) | 0.53 (0.31, 0.74) | 0.30 (0.20, 0.44) | 0 (-0.10, 0.14) | 0.50 (0.15, 0.85) | 0.72 (0.15, 0.97) | 0.02 (-0.55, 0.27) | 0.01 (-0.14, 0.20) | 0.07 (-1.83, 0.91) |
Rat self-administration | 5 | 11 | 4 | 0 | 0.75 (0.53, 0.89) | 1.0 (0.74, 1.0) | 0.44 (0.19, 0.73) | 0.69 (0.44, 0.86) | 0.44 (0.32, 0.67) | 0.14 (0.02, 0.37) | 1.0 (0.51, 1.0) | 1.0 (0.77, 1.0) | 0.3 (0.07, 0.3) | 0.19 (0.03, 0.53) | 1.0 (0.22, 1.0) |
NPV, negative predictive value; PPV, positive predictive value; PRU positive, proportionate reduction in uncertainty for positive findings; PRU negative, proportionate reduction in uncertainty for negative findings.