Dose ratios of rimonabant (ED50 value in the presence of the indicated dose of rimonabant/ED50 value in the absence of the antagonist) for all treatments used for pA2 and pKB calculations
| Drug | Dose Ratio | |||
|---|---|---|---|---|
| 0.3 | 1 | 3 | 10 | |
| Catalepsy | ||||
| A-834,735D | 1.42 | 4.41 | 9.99 | 27.99 |
| WIN55,212-2 | 2.60 | 3.21 | ||
| CP55,940 | 2.23 | 7.29 | 16.55 | |
| JWH-073 | 2.12 | |||
| CP47,497 | 1.47 | 2.83 | ||
| THC | 5.11 | |||
| Antinociception | ||||
| A-834,735D | 2.64 | 7.16 | 24.10 | 67.47 |
| WIN55,212-2 | 2.23 | 7.16 | ||
| CP55,940 | 3.06 | 9.13 | 21.02 | |
| JWH-073 | 2.99 | |||
| CP47,497 | 2.47 | 5.91 | ||
| THC | 21.2 | |||
| Hypothermia | ||||
| A-834,735D | 0 | 3.08 | 9.63 | 27.75 |
| WIN55,212-2 | 2.10 | 4.11 | ||
| CP55,940 | 3.47 | 7.57 | 27.85 | |
| JWH-073 | 2.70 | |||
| CP47,497 | 3.26 | 4.73 | ||
| THC | 10.49 | |||