TABLE 1 

Seletalisib is a potent and selective inhibitor of PI3Kδ

PI3K Isoform (n)IC50 (Fold Selectivity for PI3Kδ)
SeletalisibUCB1370037
nMnM
PI3Kδ (7–10)12 (–)2.7 (–)
PI3Kγ (4–7)282 (24x)37 (14x)
PI3Kβ (3–7)2129 (177x)78 (29x)
PI3Kα (5–7)3638 (303x)3.6 (1x)