TABLE 1

The behavioral effects of drugs of abuse in mice completely lacking βarr2

DrugDrug-Induced LocomotionLocomotor SensitizationCPP
CocaineSimilar to controlsCurrently unknownSimilar to controls
AmphetamineBlunted compared with controlsCurrently unknownCurrently unknown
MorphineBlunted compared with controlsSimilar to controlsEnhanced compared with controls
AlcoholBlunted compared with controlsCurrently unknownEnhanced compared with controls
NicotineSimilar to controls; blunted compared with controlsBlunted compared with controlsCurrently unknown
CannabinoidsCurrently unknownCurrently unknownCurrently unknown