TABLE 2

Plasma levels of vibegron in anesthetized rhesus monkeys

Values represent mean ± S.D. (N = 4–6).

Plasma Vibegron Level
nM
0.003 mg/kg0.5 ± 0.4
0.01 mg/kg1.2 ± 0.1
0.03 mg/kg3.0 ± 0.9
0.1 mg/kg13.1 ± 3.6
0.3 mg/kg43.4 ± 15.4
1 mg/kg128.5 ± 27.9
3 mg/kg553.6 ± 144.0