TABLE 1

Linear regression analysis of CYP2A6 mRNA expression (FPKM values)^{^a}^,^{^b}

Predictor Variable	B	Beta	95% CI	% Variation  Accounted for^{^c}	P Value
CYP2A69* genotype^{^d}	−117.9	−0.09	−264.8 to 25.2	0.8%	>0.1
Gender (M = 1, F = 0)	−12.0	−0.01	−118.5 to 98.5	0.01%	>0.1
AKR1D1 mRNA (FPKM)	6.0	0.4	4.3 to 7.6	16.0%	<0.001

↵^a Cases excluded pairwise.
↵^b R² = 0.17, P < 0.001.
↵^c % Variation accounted for by each variable is determined by: (Part Correlation)² × 100
↵^d CYP2A6*9 genotype coded as 0 for CYP2A6*1/*1 genotype, 1 for CYP2A6*1/*9 genotype, and 2 for CYP2A6*9/*9 genotype.