IC50 values of cationic drugs tested for interaction with OAT1 and OAT3
| Drug Name | IC50 (μM) | |
|---|---|---|
| OAT1 | OAT3 | |
| Probenecida | 2.4 | 33 |
| Darifenacin | 807 | 198 |
| Paliperidone | 1082 | 260 |
| Loperamide | No significant inhibition | 95 |
| Nebivolol | No significant inhibition | 169 |
| Halofantrine | No inhibition | No inhibition |
| Cisapride | No inhibition | No inhibition |
↵a The data for probenecid uptake inhibition is shown as a control.