TABLE 4

Percent basal surface levels and 95% confidence intervals of CB2 receptors

The results represent data obtained after treatment with select ligands (at their EC90 concentrations for inhibition of adenylyl cyclase or stimulation of arrestin recruitment).

TreatmentBasal Level (Mean ± S.E.M.)95% CI
%
Control99 ± 1.297–101
CP5594078 ± 2.374– 80
2AG99 ± 1.196–103
THC100 ± 2.492–105
HU30895 ± 3.390–103
GW833972A69 ± 3.066–72
STS13585 ± 3.376–89
UR14476 ± 2.173–80
  • CI, confidence interval; GW833972A, 2-[(3-chlorophenyl)amino]-N-(4-pyridinylmethyl)-4-(trifluoromethyl)-5-pyrimidinecarboxamide hydrochloride; HU308, 4-[4-(1,1-dimethylheptyl)-2,6-dimethoxyphenyl]-6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-methanol; THC, tetrahydrocannabinol.