TABLE 1

Summary of DCF-AG uptake kinetics mediated by OATP2B1

Each value represents the mean ± standard error of the mean from three studies (n = 2 replicates per study). *P < 0.05 for pH 6.0 versus pH 7.4.

Media pH	V_max	K_m	Uptake CL_in_t	P_dif
	pmol/min  per milligram	μM	μl/min  per milligram	μl/min  per milligram
6.0	27.8 ± 4.1*	15.2 ± 0.8	1.82 ± 0.19	0.0522 ± 0.0120*
7.4	17.6 ± 1.5	14.3 ± 0.1	1.23 ± 0.11	0.0245 ± 0.0030