TABLE 2

Effect of a T6'S mutation on inhibitor pIC50 values

AgonistΔpEC50P (H0: ΔpEC50=0)pEC50a
5-HT0.35 ± 0.073 × 10−66.00 ± 0.08
Inhibitorb
 Citral−0.36 ± 0.100.0023.55 ± 0.11
 Eucalyptol−0.45 ± 0.220.0463.14 ± 0.05
 Linalool−0.34 ± 0.045 × 10−73.51 ± 0.24
  • a Standard errors were calculated from the errors of the pEC50/pIC50 and ΔpEC50/ΔpIC50 values using propagation of error calculations.

  • b There was no significant difference between the ΔpIC50 values for the three inhibitors (P = 0.87).