Inhibitory effects of SGLT inhibitors and sitagliptin on rat GLUT and DPP4
All values are expressed as the geometric mean of two to three experiments.
| IC50 | ||
|---|---|---|
| Rat GLUT | Rat DPP4 | |
| nmol/l | ||
| Phloridzin | >10,000 | >10,000 |
| CGMI | >10,000 | >10,000 |
| Canagliflozin | >10,000a | >10,000 |
| Sitagliptin | N.D. | 12.5 |
N.D., not determined.
↵a Data from Kuriyama et al. (2014).