Potencies in the tetrad tests
Values represent ED50 (±95% CIs) in μmol/kg. All compounds were administered intraperitoneally.
| Compound | Tetrad Tests ED50 | |||
|---|---|---|---|---|
| SA | MPE | RT | RI | |
| mol. wt. | μmol/kg | |||
| Δ9-THC | 104 | 34 | 30 | 30 |
| (314) | (51–216) | (20–58) | (23–39) | (17–53) |
| AB-CHMINACA | 1.8 | 2.0 | 1.1 | 2.7 |
| (356) | (0.7–4.5) | (1.3–3.0) | (0.7–1.6) | (1.9–3.9) |
| AB-PINACA | 7.6 | 13.7 | 5.3 | 13.9 |
| (330) | (3.3–17.4) | (5.5–34.2) | (3.5–8.0) | (6.8–28.4) |
| FUBIMINA | Not active | Not active | Not active | Not active |
| (360) | (>278) | (>278) | (>278) | (>278) |
MPE, percentage of maximum possible effect in tail flick test; RI, ring immobility; RT, change in rectal temperature in °C; SA, percentage of inhibition of spontaneous activity.