Parameter estimates from modeling the dose-receptor occupancy relationship
The tracer concentration is described as a nonlinear Emax model with a baseline. The precision of the estimates is expressed as S.E. The root-mean-square error is 0.99 nM.
| Parameter | Estimate |
|---|---|
| Cnonspec,lung (nM) | 2.2 ± 0.28 |
| Cspec,max,lung (nM) | 6.4 ± 0.44 |
| Cnonspec,spleen (nM) | 2.6 ± 0.30 |
| Cspec,max,spleen (nM) | 9.6 ± 0.44 |
| ED50 (nmol/kg) | 47 ± 8.6 |