Concentrations of diclofenac and diclofenac AG in plasma of patients
See Table 1 for individual patient data.
| Patient ID Number | Time of Blood Samplinga | Diclofenac AGb | Diclofenacb |
|---|---|---|---|
| hrs | nM | ||
| N01 | 1 | N.D. | N.Q. |
| N02 | 1 | N.D. | N.Q. |
| N03 | 1 | N.Q. | 166.7 |
| N08 | 3 | 90.8 | 423.3 |
| N09 | 2.5 | N.Q. | N.Q. |
| N10 | 2.5 | N.Q. | 63.91 |
N.D., not detected (MRM signal-to-noise ratio <3 at confirmed Rt of the analyte); N.Q., not quantified (analyte concentration >lower limit of detection, <lower limit of quantification).
↵a Single blood samples were removed by venipuncture at the indicated time after the last diclofenac tablet had been taken.
↵b Diclofenac and diclofenac AG were assayed by LC-MS/MS.