TABLE 1

Summary of antagonist IC50 values at TRPA1 activation by different stimuli

AntagonistAITCOsmotic PressureCold
nM
2B10260 ± 73350 ± 6090 ± 30
2D1480 ± 50570 ± 160210 ± 58
AMG909087 ± 2875 ± 4812 ± 5