Dose | Bile Saltsa | |
---|---|---|
Day 1 | Day 10 | |
mg | μM | |
Placebo | 10.7 ± 2.4 (7.7–14) | 12.2 ± 4.0 (8.2–19) |
1 | 9.8 ± 1.7 (8.2–13) | 10.8 ± 1.2 (9.7–13) |
3 | 9.8 ± 1.4 (7.7–11) | 11.1 ± 1.6 (8.8–13) |
10 | 11.8 ± 1.2 (11–14) | 14.8 ± 2.7 (12–18) |
30 | 11.8 ± 2.7 (9.5–15) | 13.3 ± 1.4 (11–15) |
↵a Bile salts in serum were determined before dosing on both dosing days. Lower level of quantification: 1 μM.