TABLE 4

Rat plasma and rat brain protein binding measured at a single concentration of 5 μM

	Percentage bound at 5 μM
	Rat Plasma Protein^{^a}	Rat Brain Tissue^{^a}
	%
JNJ-42314415	69.0	85.4
PQ-10	98.4	99.1
MP-10	99.8	99.8

↵^a Median of three experiments.