TABLE 3

Treatment-emergent adverse events with an incidence of >1 in treatment groups after 14 days of oral dosing of JNJ-39758979

Placebo (N = 15)JNJ-39758979
30 mg per Day (N = 6)100 mg per Day (N = 5)300 mg per Day (N = 6)300 mg Twice Daily (N = 6)300 mg per Day‚Ä®(Female: N = 6)
n (%)
Abnormal feces4 (27)04 (80)2 (33)4 (67)2 (33)
Nausea2 (13)002 (33)1 (17)6 (100)
Abdominal pain2 (14)1 (17)001 (17)1 (17)
Vomiting0001 (17)01 (17)
Headache4 (27)2 (33)2 (40)1 (17)1 (17)3 (50)
Rash000002 (33)
Influenza-like illness001 (20)001 (2)
Malaise00001 (17)1 (2)
Epistaxis1 (7)1 (17)0002 (5)
Oropharyngeal pain01 (17)0001 (2)
Oral herpes01 (17)0001 (2)