Main characteristics of the patients included in the pilot clinical study
| Number of Patients | 12 (2 Women and 10 Men) |
|---|---|
| Patients characteristics | |
| Average age (yr) | 48 ± 14 |
| Mean body weight at baseline (kg) | 75.8 ± 11.9 |
| Number of nonsmokers | 6 (50%) |
| Number of smokers | 4 (33.3%) |
| Number of former smokers | 2 (16.7%) |
| Mean heart rate (beats/min) | 77.0 ± 5.4 |
| Mean blood pressure (mm Hg) | |
| Systolic | 133 ± 11 |
| Diastolic | 71 ± 8 |
| Psoriasis historic and severity | |
| Psoriasis diagnosis (yr) | >2 |
| Psoriasis Area and Severity Index score | 4–7; median, 6 |
| Body surface area (%) | 3–6; median, 5 (scale n°1) |
| Number of refractory lesions | |
| Placebo group | 11/12 (91.7%) |
| 0.86 mg/g group | 10/12 (83.3%) |
| 1.72 mg/g group | 11/12 (91.7%) |
| Lesions at the upper limb | |
| Placebo group | 7 (58.3%) |
| 0.86 mg/g group | 6 (50%) |
| 1.72 mg/g group | 8 (66.7%) |